PDB Entry - 7G5R

(Status - Released)

Summary information:

Title: Crystal Structure of rat Autotaxin in complex with 1H-benzotriazol-5-yl-[rac-(1R,2R,6S,7S)-9-[5-cyclopropyl-6-(2,2,2-trifluoroethoxy)pyridine-3-carbonyl]-4,9-diazatricyclo[5.3.0.02,6]decan-4-yl]methanone, i.e. SMILES N1(C[C@H]2[C@@H](C1)[C@H]1[C@@H]2CN(C1)C(=O)c1ccc2c(c1)N=NN2)C(=O)c1cc(c(nc1)OCC(F)(F)F)C1CC1 with IC50=0.00395687 microM

PDB DOI: https://doi.org/10.2210/pdb7g5r/pdb

Entry authors: Stihle, M., Benz, J., Hunziker, D., Mattei, P., Rudolph, M.G.

Initial deposition on: 5 June 2023

Initial release on: 18 December 2024

Latest revision on: 18 December 2024

Downloads:

Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (PDF)

Validation report (XML)

Validation report (mmCIF)

Links to more resources for 7G5R at: