PDB Entry - 7G48

(Status - Released)

Summary information:

Title: Crystal Structure of rat Autotaxin in complex with [(3aS,6aS)-5-(4-methoxynaphthalene-2-carbonyl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]-(1H-benzotriazol-5-yl)methanone, i.e. SMILES N1(C[C@@H]2[C@@H](C1)CN(C2)C(=O)c1cc(c2c(c1)cccc2)OC)C(=O)c1ccc2c(c1)N=NN2 with IC50=0.11329 microM

PDB DOI: https://doi.org/10.2210/pdb7g48/pdb

Entry authors: Stihle, M., Benz, J., Hunziker, D., Mattei, P., Rudolph, M.G.

Initial deposition on: 5 June 2023

Initial release on: 18 December 2024

Latest revision on: 18 December 2024

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (mmCIF)

Validation report (XML)

Validation report (PDF)

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