PDB Entry - 5VP0

(Status - Released)

Summary information:

Title: Discovery of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(trifluoromethoxy)phenyl]-2-methoxyethyl}-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915), A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive Disorders

PDB DOI: https://doi.org/10.2210/pdb5vp0/pdb

Primary publication DOI: https://doi.org/10.1021/acs.jmedchem.7b00807

Entry authors: Hoffman, I.D.

Initial deposition on: 3 May 2017

Initial release on: 23 August 2017

Latest revision on: 13 March 2024

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (mmCIF)

Validation report (XML)

Validation report (PDF)

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