PDB Entry - 5EI6

(Status - Released)

Summary information:

Title: Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach

PDB DOI: https://doi.org/10.2210/pdb5ei6/pdb

Primary publication DOI: https://doi.org/10.1021/acs.jmedchem.5b01811

Entry authors: Innocenti, P., Woodward, H.L., Solanki, S., Naud, N., Westwood, I.M., Cronin, N., Hayes, A., Roberts, J., Henley, A.T., Baker, R., Faisal, A., Mak, G., Box, G., Valenti, M., De Haven Brandon, A., O'Fee, L., Saville, J., Schmitt, J., Burke, R., van Montfort, R.L.M., Raymaud, F.I., Eccles, S.A., Linardopoulos, S., Blagg, J., Hoelder, S.

Initial deposition on: 29 October 2015

Initial release on: 20 April 2016

Latest revision on: 8 May 2024

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (XML)

Validation report (PDF)

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