PDB Entry - 4RRN

(Status - Released)

Summary information:

Title: 8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors

PDB DOI: https://doi.org/10.2210/pdb4rrn/pdb

Primary publication DOI: https://doi.org/10.1021/jm5015132

Entry authors: Thomas, A.A., Hunt, K.W., Newhouse, B., Watts, R.J., Liu, X., Vigers, G.P.A., Smith, D., Rhodes, S.P., Brown, K.D., Otten, J.N., Burkard, M., Cox, A.A., Geck Do, M.K., Dutcher, D., Rana, S., DeLisle, R.K., Regal, K., Wright, A.D., Groneberg, R., Liao, J., Scearce-Levie, K., Siu, M., Purkey, H.E., Lyssikatos, J.P.

Initial deposition on: 6 November 2014

Initial release on: 3 December 2014

Latest revision on: 30 October 2024

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (XML)

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Validation report (mmCIF)

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