PDB Entry - 4ANB

(Status - Released)

Summary information:

Title: Crystal structures of human MEK1 with carboxamide-based allosteric inhibitor XL518 (GDC-0973), or related analogs.

PDB DOI: https://doi.org/10.2210/pdb4anb/pdb

Primary publication DOI: https://doi.org/10.1021/ML300049D

Entry authors: Rice, K.D., Aay, N., Anand, N.K., Blazey, C.M., Bowles, O.J., Bussenius, J., Costanzo, S., Curtis, J.K., Defina, S.C., Dubenko, L., Engst, S., Joshi, A.A., Kennedy, A.R., Kim, A.I., Koltun, E.S., Lougheed, J.C., Manalo, J.C.L., Martini, J.F., Nuss, J.M., Peto, C.J., Tsang, T.H., Yu, P., Johnston, S.

Initial deposition on: 16 March 2012

Initial release on: 19 December 2012

Latest revision on: 1 May 2024

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (PDF)

Validation report (mmCIF)

Validation report (XML)

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